Quantitative comparison of the spreading and invasion of radial growth phase and metastatic melanoma cells in a three-dimensional human skin equivalent model
Background Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, proliferation and invasion in a 3D melanoma skin equi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-09-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3754.pdf |