A negative feedback loop between TET2 and leptin in adipocyte regulates body weight

A negative feedback loop between TET2 and leptin in adipocyte regulates body weight

Abstract Ten-eleven translocation (TET) 2 is an enzyme that catalyzes DNA demethylation to regulate gene expression by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine, functioning as an essential epigenetic regulator in various biological processes. However, the regulation and function of TET2...

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Bibliographic Details
Main Authors: Qin Zeng, Jianfeng Song, Xiaoxiao Sun, Dandan Wang, Xiyan Liao, Yujin Ding, Wanyu Hu, Yayi Jiao, Wuqian Mai, Wufuer Aini, Fanqi Wang, Hui Zhou, Limin Xie, Ying Mei, Yuan Tang, Zhiguo Xie, Haijing Wu, Wei Liu, Tuo Deng
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46783-x

Internet

https://doi.org/10.1038/s41467-024-46783-x

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