Astaxanthin Protects Human Granulosa Cells against Oxidative Stress through Activation of NRF2/ARE Pathway and Its Downstream Phase II Enzymes

Objective: Astaxanthin (AST) has been introduced as a radical scavenger and an anti-apoptotic factor that acts via regulating the nuclear factor-E2-related factor 2 (NRF2) and related factors. Here, we intended to examine the effect of AST on granulosa cells (GCs) against oxidative stress by exami...

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Bibliographic Details
Main Authors: Mojtaba Eslami, Sahar Esfandyari, Marzieh Aghahosseini, Zahra Rashidi, Shirzad Hosseinishental, Samane Brenjian, Aligholi Sobhani, Fardin Amidi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2021-08-01
Series:Cell Journal
Subjects:
Online Access:https://celljournal.org/journal/article/fulltext/astaxanthin-protects-human-granulosa-cells-against-oxidative-stress-through-activation-of-nrf2are-pathway-and-its-downstream-phase-ii-enzymes.pdf