Trichinella spiralis cathepsin L damages the tight junctions of intestinal epithelial cells and mediates larval invasion.

Trichinella spiralis cathepsin L damages the tight junctions of intestinal epithelial cells and mediates larval invasion.

<h4>Background</h4>Cathepsin L, a lysosomal enzyme, participates in diverse physiological processes. Recombinant Trichinella spiralis cathepsin L domains (rTsCatL2) exhibited natural cysteine protease activity and hydrolyzed host immunoglobulin and extracellular matrix proteins in vitro,...

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Bibliographic Details
Main Authors: Ruo Dan Liu, Xiang Yu Meng, Chen Le Li, Xin Zhi Lin, Qiu Yi Xu, Han Xu, Shao Rong Long, Jing Cui, Zhong Quan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011816&type=printable

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https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011816&type=printable

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