No Effect of Diet-Induced Mild Hyperhomocysteinemia on Vascular Methylating Capacity, Atherosclerosis Progression, and Specific Histone Methylation

No Effect of Diet-Induced Mild Hyperhomocysteinemia on Vascular Methylating Capacity, Atherosclerosis Progression, and Specific Histone Methylation

Hyperhomocysteinemia (HHcy) is a risk factor for atherosclerosis through mechanisms which are still incompletely defined. One possible mechanism involves the hypomethylation of the nuclear histone proteins to favor the progression of atherosclerosis. In previous cell studies, hypomethylating stress...

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Bibliographic Details
Main Authors: Courtney A. Whalen, Floyd J. Mattie, Cristina Florindo, Bertrand van Zelst, Neil K. Huang, Isabel Tavares de Almeida, Sandra G. Heil, Thomas Neuberger, A. Catharine Ross, Rita Castro
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Nutrients
Subjects:
homocysteine and vascular disease
H3K27me3
epigenetics
atherosclerosis
MRI (magnetic resonance imaging)
Online Access:https://www.mdpi.com/2072-6643/12/8/2182

Internet

https://www.mdpi.com/2072-6643/12/8/2182

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