Optimization of Mesoporous Silica Nanoparticles through Statistical Design of Experiment and the Application for the Anticancer Drug

Optimization of Mesoporous Silica Nanoparticles through Statistical Design of Experiment and the Application for the Anticancer Drug

The synthesis process or composition of mesoporous silica nanoparticles (MSNs) affects the physicochemical properties. Using these properties, MSNs were synthesized through the Box–Behnken design (BBD) among statistical experimental methods. The effect of the amounts of synthetic reagents, hexadecyl...

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Bibliographic Details
Main Authors: Min-Ki Kim, Do-Hyung Ki, Young-Guk Na, Hae-Soo Lee, Jong-Suep Baek, Jae-Young Lee, Hong-Ki Lee, Cheong-Weon Cho
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
mesoporous silica nanoparticles
doxorubicin
design of experiment
Box–Behnken design
optimization
Online Access:https://www.mdpi.com/1999-4923/13/2/184

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https://www.mdpi.com/1999-4923/13/2/184

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