Apelin is expressed in intimal smooth muscle cells and promotes their phenotypic transition
Abstract During atherosclerotic plaque formation, smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype. We previously isolated differentiated spindle-shaped (S) and dedifferentiated rhomboid (R) SMCs from porcine coronary artery. R-SMCs expres...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-45470-z |