Effect of Enterococcus faecalis 2001 on colitis and depressive-like behavior in dextran sulfate sodium-treated mice: involvement of the brain–gut axis

Abstract Background Patients with inflammatory bowel disease (IBD), including those with ulcerative colitis and Crohn’s disease, have higher rates of psychiatric disorders, such as depression and anxiety; however, the mechanism of psychiatric disorder development remains unclear. Mice with IBD induc...

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Main Authors: Kohei Takahashi, Osamu Nakagawasai, Wataru Nemoto, Takayo Odaira, Wakana Sakuma, Hiroshi Onogi, Hiroaki Nishijima, Ryuji Furihata, Yukio Nemoto, Hiroyuki Iwasa, Koichi Tan-No, Takeshi Tadano
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-019-1580-7