Metal Binding Properties of the N-Terminus of the Functional Amyloid Orb2

Metal Binding Properties of the N-Terminus of the Functional Amyloid Orb2

The cytoplasmic polyadenylation element binding protein (CPEB) homologue Orb2 is a functional amyloid that plays a key regulatory role for long-term memory in Drosophila. Orb2 has a glutamine, histidine-rich (Q/H-rich) domain that resembles the Q/H-rich, metal binding domain of the Hpn-like protein...

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Bibliographic Details
Main Authors: Thalia H. Bajakian, Silvia A. Cervantes, Maria A. Soria, Maïwenn Beaugrand, Ji Yun Kim, Rachel J. Service, Ansgar B. Siemer
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Biomolecules
Subjects:
amyloid
protein–metal interaction
aggregation
ITC
thioflavin T fluorescence
Online Access:https://www.mdpi.com/2218-273X/7/3/57

Internet

https://www.mdpi.com/2218-273X/7/3/57

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