Toxoplasma Shelph, a Phosphatase Located in the Parasite Endoplasmic Reticulum, Is Required for Parasite Virulence

Toxoplasma Shelph, a Phosphatase Located in the Parasite Endoplasmic Reticulum, Is Required for Parasite Virulence

ABSTRACT Toxoplasma gondii is a single-celled parasitic eukaryote that evolved to successfully propagate in any nucleated cell. As with any other eukaryote, its life cycle is regulated by signaling pathways controlled by kinases and phosphatases. T. gondii encodes an atypical bacterial-like phosphat...

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Bibliographic Details
Main Authors: Rania Najm, Maguy Hamie, Laurence Berry-Sterkers, Maryse Lebrun, Hiba El Hajj, Mauld H. Lamarque
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mSphere
Subjects:
Toxoplasma gondii
enzyme kinetics
infectious disease
parasitology
reverse genetic analysis
serine/threonine phosphatases
Online Access:https://journals.asm.org/doi/10.1128/msphere.00350-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00350-22

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