Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibition

Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibition

Context M2 phenotype macrophage polarization is an attractive target for therapeutic intervention. Asiaticoside (ATS) has multiple pharmacological functions.Objective This study investigates the effect of ATS on M2 phenotype macrophage polarization in osteosarcoma.Materials and methods The different...

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Bibliographic Details
Main Authors: Dang-ke Li, Guang-hui Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Tumour necrosis factor receptor-associated factor 6
viability
invasion
THP-1
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2109688

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2022.2109688

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