Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agentsResearch in context

Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agentsResearch in context

Summary: Background: Ischemia of the bile duct is a common feature in liver disease and transplantation, which represents a major cause of morbidity and mortality, especially after liver transplantation. Detailed knowledge of its pathogenesis remains incomplete due to the lack of appropriate in vit...

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Bibliographic Details
Main Authors: Shaojun Shi, Henk P. Roest, Thierry P.P. van den Bosch, Marcel J.C. Bijvelds, Markus U. Boehnert, Jeroen de Jonge, Sven O. Dekker, Antoine A.F. de Vries, Hugo R. de Jonge, Monique M.A. Verstegen, Luc J.W. van der Laan
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:EBioMedicine
Subjects:
Ischemia-reperfusion injury
Biliary injury
Liver transplantation
Organoid
Drug screening
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422006132

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http://www.sciencedirect.com/science/article/pii/S2352396422006132

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