Functionally active TRPA1 ion channel is downregulated in peptidergic neurons of the Edinger-Westphal nucleus upon acute alcohol exposure

Functionally active TRPA1 ion channel is downregulated in peptidergic neurons of the Edinger-Westphal nucleus upon acute alcohol exposure

Introduction: The centrally projecting Edinger-Westphal nucleus (EWcp) contributes to the control of alcohol consumption by its urocortin 1 (UCN1) and cocaine- and amphetamine-regulated transcript (CART) co-expressing peptidergic neurons. Our group recently showed that the urocortinergic centrally p...

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Bibliographic Details
Main Authors: Ammar Al-Omari, Miklós Kecskés, Balázs Gaszner, Tünde Biró-Sütő, Balázs Fazekas, Gergely Berta, Mónika Kuzma, Erika Pintér, Viktória Kormos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
alcohol
centrally projecting Edinger-Westphal nucleus
transient receptor potential ankyrin 1
urocortin 1
cocaine-and amphetamine-regulated transcript
JT010
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1046559/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1046559/full

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