Mycobacterium bovis BCG as immunostimulating agent prevents the severe form of chronic experimental Chagas disease

Mycobacterium bovis BCG as immunostimulating agent prevents the severe form of chronic experimental Chagas disease

IntroductionThere is currently no vaccine against Chagas disease (ChD), and the medications available confer multiple side effects. Mycobacterium bovis Bacillus Calmette–Guérin (BCG) produces balanced Th1, Th2, and Th17 modulatory immune responses and has improved efficacy in controlling chronic inf...

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Bibliographic Details
Main Authors: Minerva Arce-Fonseca, Dulce Mata-Espinosa, Alberto Aranda-Fraustro, José Luis Rosales-Encina, Mario Alberto Flores-Valdez, Olivia Rodríguez-Morales
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
Chagas disease
Trypanosoma cruzi
BCG
vaccination
trained/nonspecific immunity
immunomodulator
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380049/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380049/full

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