Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.

Small Rho GTPases are well known to regulate a variety of cellular processes by acting as molecular switches. The regulatory function of Rho GTPases is critically dependent on their posttranslational modification at the carboxyl terminus by isoprenylation and association with proper cellular membran...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Si-Cai Zhang, Lothar Gremer, Henrike Heise, Petra Janning, Aliaksei Shymanets, Ion C Cirstea, Eberhard Krause, Bernd Nürnberg, Mohammad Reza Ahmadian
Format: Artykuł
Język:English
Wydane: Public Library of Science (PLoS) 2014-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC4094549?pdf=render