Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.
Small Rho GTPases are well known to regulate a variety of cellular processes by acting as molecular switches. The regulatory function of Rho GTPases is critically dependent on their posttranslational modification at the carboxyl terminus by isoprenylation and association with proper cellular membran...
Główni autorzy: | , , , , , , , , |
---|---|
Format: | Artykuł |
Język: | English |
Wydane: |
Public Library of Science (PLoS)
2014-01-01
|
Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC4094549?pdf=render |