Bone marrow stromal cells in Modic type 1 changes promote neurite outgrowth

Bone marrow stromal cells in Modic type 1 changes promote neurite outgrowth

The pain in patients with Modic type 1 changes (MC1) is often due to vertebral body endplate pain, which is linked to abnormal neurite outgrowth in the vertebral body and adjacent endplate. The aim of this study was to understand the role of MC1 bone marrow stromal cells (BMSCs) in neurite outgrowth...

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Bibliographic Details
Main Authors: Tamara Mengis, Nick Herger, Irina Heggli, Jan Devan, José Miguel Spirig, Christoph J. Laux, Florian Brunner, Mazda Farshad, Oliver Distler, Stefan Dudli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
low back pain
neurotrophic
stromal cells
Modic changes
neurite outgrowth
basivertebral nerve
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1286280/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1286280/full

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