Gastrodin overcomes chemoresistance via inhibiting Skp2-mediated glycolysis
Abstract Aerobic glycolysis, a typical phenotype in human tumors, is associated with tumor progression and chemotherapy resistance. The present study demonstrated that cisplatin-resistant oral squamous cell carcinoma (OSCC) cells exerted a stronger glycolysis ability, which was associated with hexok...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-10-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01648-y |