Modern methods of preclinical anticancer drug screening using test systems based on cell cultures

Modern methods of preclinical anticancer drug screening using test systems based on cell cultures

Preclinical screening of medicinal drugs for novel anti-cancer treatments faces a problem of a rational approach to primary screening of substances with antitumor activity. Low correlation between in vitro and in vivo studies with clinical trials remains a serious issue. Choosing the right tumor mod...

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Bibliographic Details
Main Authors: K.V. Kitaeva, A.A. Rizvanov, V.V. Solovyeva
Format: Article
Language:English
Published: Kazan Federal University 2021-06-01
Series:Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki
Subjects:
antitumor drug screening
in vitro tumor model
two-dimensional cultures
three-dimensional cultures
microfluidic systems
boyden chamber
tumor microenvironment
3d bioprinting
Online Access:https://kpfu.ru/uz-eng-ns-2021-2-1.html

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