Plasma IAPP-Autoantibody Levels in Alzheimer’s Disease Patients Are Affected by <i>APOE4</i> Status

Plasma IAPP-Autoantibody Levels in Alzheimer’s Disease Patients Are Affected by <i>APOE4</i> Status

Pancreas-derived islet amyloid polypeptide (IAPP) crosses the blood–brain barrier and co-deposits with amyloid beta (Aβ) in brains of type 2 diabetes (T2D) and Alzheimer’s disease (AD) patients. Depositions might be related to the circulating IAPP levels, but it warrants further investigation. Autoa...

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Bibliographic Details
Main Authors: Dovilė Pocevičiūtė, Bodil Roth, Nina Schultz, Cristina Nuñez-Diaz, Shorena Janelidze, The Netherlands Brain Bank, Anders Olofsson, Oskar Hansson, Malin Wennström
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
AD
amylin
amyloid beta
<i>APOE4</i>
autoantibodies
cognition
Online Access:https://www.mdpi.com/1422-0067/24/4/3776

Internet

https://www.mdpi.com/1422-0067/24/4/3776

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