Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats
Reduced glomerular filtration, hypertension and renal microvascular injury are hallmarks of chronic kidney disease, which has a global prevalence of ~10%. We have shown previously shown that the Fischer (F344) rat has lower GFR than the Lewis rat, and is more susceptible to renal injury induced by h...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-10-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00305/full |