Dose-related immunomodulatory effects of recombinant TRAIL in the tumor immune microenvironment

Dose-related immunomodulatory effects of recombinant TRAIL in the tumor immune microenvironment

Abstract Background In addition to specifically inducing tumor cell apoptosis, recombinant tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) has also been reported to influence the cancer immune microenvironment; however, its underlying effects and mechanisms remain unclear. Inve...

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Bibliographic Details
Main Authors: Xupu Wang, Lizheng Wang, Wenmo Liu, Xinyao Liu, Xinyuan Jia, Xinyao Feng, Fangshen Li, Rui Zhu, Jiahao Yu, Haihong Zhang, Hui Wu, Jiaxin Wu, Chu Wang, Bin Yu, Xianghui Yu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TRAIL
Immunoregulation
Tumor-associated macrophage
Online Access:https://doi.org/10.1186/s13046-023-02795-x

Internet

https://doi.org/10.1186/s13046-023-02795-x

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