Modest Effects of Osteoclast‐Specific ERα Deletion after Skeletal Maturity

Modest Effects of Osteoclast‐Specific ERα Deletion after Skeletal Maturity

ABSTRACT Estrogen regulates bone mass in women and men, but the underlying cellular mechanisms of estrogen action on bone remain unclear. Although both estrogen receptor (ER)α and ERβ are expressed in bone cells, ERα is the dominant receptor for skeletal estrogen action. Previous studies using eithe...

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Bibliographic Details
Main Authors: Madison L. Doolittle, Brittany A. Eckhardt, Stephanie J. Vos, Sarah Grain, Jennifer L. Rowsey, Ming Ruan, Dominik Saul, Joshua N. Farr, Megan M. Weivoda, Sundeep Khosla, David G. Monroe
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:JBMR Plus
Subjects:
ESTROGENS AND SELECTIVE ESTROGEN RECEPTOR MODULATOR
GENETIC ANIMAL MODELS
OSTEOCLASTS
OSTEOPOROSIS
SEX STEROIDS
Online Access:https://doi.org/10.1002/jbm4.10797

Internet

https://doi.org/10.1002/jbm4.10797

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