Regulation of miRNA transcription in macrophages in response to Candida albicans.

Macrophages detect pathogens via pattern recognition receptors (PRRs), which trigger several intracellular signaling cascades including the MAPK and NFκB pathways. These in turn mediate the up-regulation of pro-inflammatory cytokines that are essential to combat the pathogen. However as the over-pro...

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Bibliographic Details
Main Authors: Claire E Monk, György Hutvagner, J Simon C Arthur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21060679/?tool=EBI