Production of a Foot-and-Mouth Disease Vaccine Antigen Using Suspension-Adapted BHK-21 Cells in a Bioreactor

Production of a Foot-and-Mouth Disease Vaccine Antigen Using Suspension-Adapted BHK-21 Cells in a Bioreactor

The baby hamster kidney-21 (BHK-21) cell line is a continuous cell line used to propagate foot-and-mouth disease (FMD) virus for vaccine manufacturing. BHK-21 cells are anchorage-dependent, although suspension cultures would enable rapid growth in bioreactors, large-scale virus propagation, and cost...

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Bibliographic Details
Main Authors: Soonyong Park, Ji Yul Kim, Kyoung-Hwa Ryu, Ah-Young Kim, Jaemun Kim, Young-Joon Ko, Eun Gyo Lee
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Vaccines
Subjects:
adherent
baby hamster kidney cell
foot-and-mouth disease
virus productivity
suspension culture
vaccine
Online Access:https://www.mdpi.com/2076-393X/9/5/505

Internet

https://www.mdpi.com/2076-393X/9/5/505

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