The breadth, but not the magnitude, of circulating memory B cell responses to P. falciparum increases with age/exposure in an area of low transmission.

The breadth, but not the magnitude, of circulating memory B cell responses to P. falciparum increases with age/exposure in an area of low transmission.

BACKGROUND:Malaria caused by Plasmodium falciparum remains a major cause of death in sub-Saharan Africa. Immunity against symptoms of malaria requires repeated exposure, suggesting either that the parasite is poorly immunogenic or that the development of effective immune responses to malaria may be...

Full description

Bibliographic Details
Main Authors: Sarah I Nogaro, Julius C Hafalla, Brigitte Walther, Edmond J Remarque, Kevin K A Tetteh, David J Conway, Eleanor M Riley, Michael Walther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3186790?pdf=render

Internet

http://europepmc.org/articles/PMC3186790?pdf=render

Similar Items