Evaluation of multigene assays as predictors for response to neoadjuvant chemotherapy in early-stage breast cancer patients

Abstract OncotypeDX and MammaPrint assays have not been validated to predict pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) in early-stage breast cancer patients. We analyzed the 2010–2019 National Cancer Database and found that high OncotypeDX recurrence scores or high MammaP...

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Bibliographic Details
Main Authors: Jincong Q. Freeman, Sarah Shubeck, Frederick M. Howard, Nan Chen, Rita Nanda, Dezheng Huo
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00536-z