Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction

Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction

The primary function of selenophosphate synthetase (SEPHS) is to catalyze the synthesis of selenophosphate that serves as a selenium donor during selenocysteine synthesis. In eukaryotes, there are two isoforms of SEPHS (SEPHS1 and SEPHS2). Between these two isoforms, only SEPHS2 is known to contain...

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Bibliographic Details
Main Authors: Jisu Jung, Yoomin Kim, Jiwoon Na, Lu Qiao, Jeyoung Bang, Dongin Kwon, Tack-Jin Yoo, Donghyun Kang, Lark Kyun Kim, Bradley A. Carlson, Dolph L. Hatfield, Jin-Hong Kim, Byeong Jae Lee
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
selenium
selenoprotein
selenophosphate synthetase
endothelial cell
reactive oxygen species
cell growth
Online Access:https://www.mdpi.com/1422-0067/22/21/11646

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https://www.mdpi.com/1422-0067/22/21/11646

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