The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (<i>ppp1r14</i>) Family of Protein Phosphatase 1 Inhibitors in Teleosts

The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (<i>ppp1r14</i>) Family of Protein Phosphatase 1 Inhibitors in Teleosts

The Cpi-17 (<i>ppp1r14</i>) gene family is an evolutionarily conserved, vertebrate specific group of protein phosphatase 1 (PP1) inhibitors. When phosphorylated, Cpi-17 is a potent inhibitor of myosin phosphatase (MP), a holoenzyme complex of the regulatory subunit Mypt1 and the catalyti...

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Bibliographic Details
Main Authors: Irene Lang, Guneet Virk, Dale C. Zheng, Jason Young, Michael J. Nguyen, Rojin Amiri, Michelle Fong, Alisa Arata, Katia S. Chadaideh, Susan Walsh, Douglas C. Weiser
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Danio rerio
Phi-1 (ppp1r14b)
Cpi-17 (ppp1r14a)
PP1
Mypt1
genome duplication
Online Access:https://www.mdpi.com/1422-0067/21/16/5709

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https://www.mdpi.com/1422-0067/21/16/5709

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