Impaired islet function and normal exocrine enzyme secretion occur with low inter-regional variation in type 1 diabetes

Summary: Histopathological heterogeneity in the human pancreas is well documented; however, functional evidence at the tissue level is scarce. Herein, we investigate in situ glucose-stimulated islet and carbachol-stimulated acinar cell secretion across the pancreas head (PH), body (PB), and tail (PT...

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Bibliografische gegevens
Hoofdauteurs: Denise M. Drotar, Ana Karen Mojica-Avila, Drew T. Bloss, Christian M. Cohrs, Cameron T. Manson, Amanda L. Posgai, MacKenzie D. Williams, Maigan A. Brusko, Edward A. Phelps, Clive H. Wasserfall, Stephan Speier, Mark A. Atkinson
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2024-06-01
Reeks:Cell Reports
Onderwerpen:
Online toegang:http://www.sciencedirect.com/science/article/pii/S2211124724006740