Detailed characterization of the transcriptome of single B cells in mantle cell lymphoma suggesting a potential use for SOX4

Abstract Mantle cell lymphoma (MCL) is a malignancy arising from naive B lymphocytes with common bone marrow (BM) involvement. Although t(11;14) is a primary event in MCL development, the highly diverse molecular etiology and causal genomic events are still being explored. We investigated the transc...

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Bibliographic Details
Main Authors: Simone Valentin Hansen, Marcus Høy Hansen, Oriane Cédile, Michael Boe Møller, Jacob Haaber, Niels Abildgaard, Charlotte Guldborg Nyvold
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98560-1