Scutellarin Rescued Mitochondrial Damage through Ameliorating Mitochondrial Glucose Oxidation via the Pdk‐Pdc Axis

Scutellarin Rescued Mitochondrial Damage through Ameliorating Mitochondrial Glucose Oxidation via the Pdk‐Pdc Axis

Abstract Mitochondrial bioenergetic deficits and their resulting glucose hypometabolism are the key pathophysiological modulators that promote neurodegeneration. However, there are no specific potential molecules that have been identified to treat neurological diseases by regulating energy metabolis...

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Bibliographic Details
Main Authors: Ning Sheng, Zhihui Zhang, Hao Zheng, Congyu Ma, Menglin Li, Zhe Wang, Lulu Wang, Jiandong Jiang, Jinlan Zhang
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Advanced Science
Subjects:
13C metabolic flux analysis
mitochondria
proteomics
pyruvate dehydrogenase kinase
scutellarin
Online Access:https://doi.org/10.1002/advs.202303584

Internet

https://doi.org/10.1002/advs.202303584

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