Characterization of the human <i>IDH1</i> gene promoter

In cancer, the production of ATP depends mainly on glycolysis, usually accompanied by the dysfunction of the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS). Nicotinamide adenine dinucleotide (NAD<sup>+</sup>) is a coenzyme for various biological enzymatic reactions...

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Main Authors: Yutaka Takihara, Ryuji Otani, Takuro Ishii, Shunsuke Takaoka, Yuki Nakano, Kaori Inoue, Steven Larsen, Yoko Ogino, Masashi Asai, Sei-ichi Tanuma, Fumiaki Uchiumi
Format: Article
Language:English
Published: AIMS Press 2023-08-01
Series:AIMS Molecular Science
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Online Access:https://www.aimspress.com/article/doi/10.3934/molsci.2023013