Accurate prediction of protein folding mechanisms by simple structure-based statistical mechanical models

Abstract Recent breakthroughs in highly accurate protein structure prediction using deep neural networks have made considerable progress in solving the structure prediction component of the ‘protein folding problem’. However, predicting detailed mechanisms of how proteins fold into specific native s...

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Bibliographic Details
Main Authors: Koji Ooka, Munehito Arai
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41664-1