CRISPR-Cas Controls Cryptic Prophages

The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, <i>Escherichia coli</i> K-12. We show here that the <i>E. coli</i> CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) proph...

Full description

Bibliographic Details
Main Authors: Sooyeon Song, Ekaterina Semenova, Konstantin Severinov, Laura Fernández-García, Michael J. Benedik, Toshinari Maeda, Thomas K. Wood
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/24/16195