A Methodological Framework to Discover Pharmacogenomic Interactions Based on Random Forests

A Methodological Framework to Discover Pharmacogenomic Interactions Based on Random Forests

The identification of genomic alterations in tumor tissues, including somatic mutations, deletions, and gene amplifications, produces large amounts of data, which can be correlated with a diversity of therapeutic responses. We aimed to provide a methodological framework to discover pharmacogenomic i...

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Bibliographic Details
Main Authors: Salvatore Fasola, Giovanna Cilluffo, Laura Montalbano, Velia Malizia, Giuliana Ferrante, Stefania La Grutta
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
cancer
cell lines
drug response
genomic alterations
pharmacogenomic interactions
Random Forests
Online Access:https://www.mdpi.com/2073-4425/12/6/933

Internet

https://www.mdpi.com/2073-4425/12/6/933

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