Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation

Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has prompted great interest in novel broad-spectrum antivirals, including perylene-related compounds. In the present study, we performed a structure–activity relationship analysi...

Full description

Bibliographic Details
Main Authors: Petra Straková, Petr Bednář, Jan Kotouček, Jiří Holoubek, Andrea Fořtová, Pavel Svoboda, Michal Štefánik, Ivana Huvarová, Pavlína Šimečková, Josef Mašek, Daniil A. Gvozdev, Igor E. Mikhnovets, Alexey A. Chistov, Timofei D. Nikitin, Maxim S. Krasilnikov, Alexey V. Ustinov, Vera A. Alferova, Vladimir A. Korshun, Daniel Růžek, Luděk Eyer
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Virus Research
Subjects:
SARS-CoV-2
Perylene-related compound
Antiviral activity
Membrane
Liposome
Photodynamic inactivation
Online Access:http://www.sciencedirect.com/science/article/pii/S016817022300120X

Internet

http://www.sciencedirect.com/science/article/pii/S016817022300120X

Similar Items