A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging

Summary: The complex functions of neuronal synapses depend on their tightly interconnected protein network, and their dysregulation is implicated in the pathogenesis of autism spectrum disorders and schizophrenia. However, it remains unclear how synaptic molecular networks are altered biochemically...

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Bibliographic Details
Main Authors: Reuven Falkovich, Eric W. Danielson, Karen Perez de Arce, Eike-C. Wamhoff, Juliana Strother, Anna P. Lapteva, Morgan Sheng, Jeffrey R. Cottrell, Mark Bathe
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004412