Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse definitive endoderm differentiation revealed by microRNA profiling.

Generation of hepatocyte from embryonic stem cells (ESCs) holds great promise for hepatocyte replacement therapy to treat liver diseases. Achieving high efficiency of directed differentiation of ESCs to hepatocyte is of critical importance. Previously, Wnt3a has been reported to promote Activin A-in...

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Bibliographic Details
Main Authors: Shijun Fu, Qi Fei, Hua Jiang, Shannon Chuai, Song Shi, Wen Xiong, Lei Jiang, Chris Lu, Peter Atadja, En Li, Jianyong Shou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3223193?pdf=render