Puerarin-V Improve Mitochondrial Respiration and Cardiac Function in a Rat Model of Diabetic Cardiomyopathy via Inhibiting Pyroptosis Pathway through P2X7 Receptors

Puerarin-V Improve Mitochondrial Respiration and Cardiac Function in a Rat Model of Diabetic Cardiomyopathy via Inhibiting Pyroptosis Pathway through P2X7 Receptors

There is a new form of puerarin, puerarin-V, that has recently been developed, and it is unclear whether puerarin-V has a cardioprotective effect on diabetic cardiomyopathy (DCM). Here, we determined whether puerarin-V had any beneficial influence on the pathophysiology of DCM and explored its possi...

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Bibliographic Details
Main Authors: Shuchan Sun, Awaguli Dawuti, Difei Gong, Ranran Wang, Tianyi Yuan, Shoubao Wang, Cheng Xing, Yang Lu, Guanhua Du, Lianghua Fang
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
puerarin-V
diabetic cardiomyopathy
mitochondrial
pyroptosis
P2X7 receptors
Online Access:https://www.mdpi.com/1422-0067/23/21/13015

Internet

https://www.mdpi.com/1422-0067/23/21/13015

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