Cholesterol Accumulation as a Driver of Hepatic Inflammation Under Translational Dietary Conditions Can Be Attenuated by a Multicomponent Medicine

BackgroundNon-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is characterised by dysfunctional lipid metabolism and cholesterol homeostasis, and a related chronic inflammatory response. NAFLD has become the most common cause of chronic liver disease in many countries...

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Main Authors: Andrea M. Mueller, Robert Kleemann, Eveline Gart, Wim van Duyvenvoorde, Lars Verschuren, Martien Caspers, Aswin Menke, Natascha Krömmelbein, Kanita Salic, Yvonne Burmeister, Bernd Seilheimer, Martine C. Morrison
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.601160/full