Risk of hepatotoxicity with trastuzumab emtansine in breast cancer patients: a systematic review and meta-analysis

Background: Trastuzumab emtansine (T-DM1) is an anti-HER2 antibody-drug conjugate indicated for the treatment of HER2-positive breast cancer. One of the most severe adverse events reported with T-DM1 is hepatotoxicity. The objective of our meta-analysis is to investigate the risk of hepatic adverse...

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Bibliographic Details
Main Authors: Amani M. Cobert, Catherine Helms, Chris Larck, Donald C. Moore
Format: Article
Language:English
Published: SAGE Publishing 2020-04-01
Series:Therapeutic Advances in Drug Safety
Online Access:https://doi.org/10.1177/2042098620915058