High-flow nasal cannula for respiratory failure in adult patients

The high-flow nasal cannula (HFNC) has been recently used in several clinical settings for oxygenation in adults. In particular, the advantages of HFNC compared with low-flow oxygen systems or non-invasive ventilation include enhanced comfort, increased humidification of secretions to facilitate exp...

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Main Author: SeungYong Park
Format: Article
Language:English
Published: Korean Society of Critical Care Medicine 2021-11-01
Series:Acute and Critical Care
Subjects:
Online Access:http://www.accjournal.org/upload/pdf/acc-2021-01571.pdf
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author SeungYong Park
author_facet SeungYong Park
author_sort SeungYong Park
collection DOAJ
description The high-flow nasal cannula (HFNC) has been recently used in several clinical settings for oxygenation in adults. In particular, the advantages of HFNC compared with low-flow oxygen systems or non-invasive ventilation include enhanced comfort, increased humidification of secretions to facilitate expectoration, washout of nasopharyngeal dead space to improve the efficiency of ventilation, provision of a small positive end-inspiratory pressure effect, and fixed and rapid delivery of an accurate fraction of inspired oxygen (FiO2) by minimizing the entrainment of room air. HFNC has been successfully used in critically ill patients with several conditions, such as hypoxemic respiratory failure, hypercapneic respiratory failure (exacerbation of chronic obstructive lung disease), post-extubation respiratory failure, pre-intubation oxygenation, and others. However, the indications are not absolute, and much of the proven benefit remains subjective and physiologic. This review discusses the practical application and clinical uses of HFNC in adults, including its unique respiratory physiologic effects, device settings, and clinical indications.
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spelling doaj.art-fd1071438e7b4fc3a983f726dfc95e6b2022-12-22T00:58:53ZengKorean Society of Critical Care MedicineAcute and Critical Care2586-60522586-60602021-11-0136427528510.4266/acc.2021.015711338High-flow nasal cannula for respiratory failure in adult patientsSeungYong Park0 Division of Respiratory, Allergy and Critical Care Medicine, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, KoreaThe high-flow nasal cannula (HFNC) has been recently used in several clinical settings for oxygenation in adults. In particular, the advantages of HFNC compared with low-flow oxygen systems or non-invasive ventilation include enhanced comfort, increased humidification of secretions to facilitate expectoration, washout of nasopharyngeal dead space to improve the efficiency of ventilation, provision of a small positive end-inspiratory pressure effect, and fixed and rapid delivery of an accurate fraction of inspired oxygen (FiO2) by minimizing the entrainment of room air. HFNC has been successfully used in critically ill patients with several conditions, such as hypoxemic respiratory failure, hypercapneic respiratory failure (exacerbation of chronic obstructive lung disease), post-extubation respiratory failure, pre-intubation oxygenation, and others. However, the indications are not absolute, and much of the proven benefit remains subjective and physiologic. This review discusses the practical application and clinical uses of HFNC in adults, including its unique respiratory physiologic effects, device settings, and clinical indications.http://www.accjournal.org/upload/pdf/acc-2021-01571.pdfhigh-flow nasal cannulaoxygenrespiratory failure
spellingShingle SeungYong Park
High-flow nasal cannula for respiratory failure in adult patients
Acute and Critical Care
high-flow nasal cannula
oxygen
respiratory failure
title High-flow nasal cannula for respiratory failure in adult patients
title_full High-flow nasal cannula for respiratory failure in adult patients
title_fullStr High-flow nasal cannula for respiratory failure in adult patients
title_full_unstemmed High-flow nasal cannula for respiratory failure in adult patients
title_short High-flow nasal cannula for respiratory failure in adult patients
title_sort high flow nasal cannula for respiratory failure in adult patients
topic high-flow nasal cannula
oxygen
respiratory failure
url http://www.accjournal.org/upload/pdf/acc-2021-01571.pdf
work_keys_str_mv AT seungyongpark highflownasalcannulaforrespiratoryfailureinadultpatients