DNA binding, cleavage and anticancer activity of a Zn(II)-Cu(II) hetero-dinuclear carbohydrazone complex containing the secondary ligand 1,10-phenanthroline
A hetero di-nuclear complex [Zn(o-phen)LCu(OAc)] (1) (H3L = o-HOC6H4CH = NNH)2C = O, o-phen = 1,10-phenanthroline) exhibited intercalative DNA binding (Kb = 1.03 × 105 M−1) as revealed from UV–Vis spectral analysis as well as viscosity study and further supported by molecular docking study of 1 with...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-12-01
|
| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221171562300348X |