Repurposing of dextromethorphan as an adjunct therapy in patients with major depressive disorder: a randomised, group sequential adaptive design, controlled clinical trial protocol

Background Therapeutic latency, lack of efficacy and adverse drug reactions are the major concerns in current antidepressant therapies. To overcome these treatment hurdles, add-on therapy to conventional antidepressant medications may lead to better therapeutic outcomes. The present randomised contr...

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Bibliographic Details
Main Authors: Shampa Maji, Rituparna Maiti, Anand Srinivasan, Debadatta Mohapatra, Monalisa Jena
Format: Article
Language:English
Published: BMJ Publishing Group 2024-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/4/e080500.full