Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses <i>MXRA8</i> Levels and Impairs Breast Cancer Growth and Metastasis In Vivo

Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses <i>MXRA8</i> Levels and Impairs Breast Cancer Growth and Metastasis In Vivo

Breast cancer cells with mesenchymal characteristics, particularly the claudin-low subtype, express extremely low levels of miR-200s. Therefore, this study examined the functional impact of restoring miR-200 expression in a human claudin-low breast cancer cell line MDA-MB-231. MDA-MB-231 cells were...

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Bibliographic Details
Main Authors: Kaitlyn E. Simpson, Katrina L. Watson, Roger A. Moorehead
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
miR-200
claudin-low breast cancer
tumor growth
metastasis
<i>MXRA8</i>
MDA-MB-231
Online Access:https://www.mdpi.com/2073-4425/13/4/691

Internet

https://www.mdpi.com/2073-4425/13/4/691

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