MiR-483-5p downregulation alleviates ox-LDL induced endothelial cell injury in atherosclerosis

MiR-483-5p downregulation alleviates ox-LDL induced endothelial cell injury in atherosclerosis

Abstract Background In light of the abnormal expression of microRNA (miR-483-5p) in patients with atherosclerosis (AS), its role in vascular endothelial cell injury was explored. And the mechanisms related to autophagy were also elucidated. Methods Human umbilical vein endothelial cells (HUVECs) wer...

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Bibliographic Details
Main Authors: Hezhong Zhu, Hui Liang, Zhen Gao, Xiaoqiao Zhang, Qian He, Chaoyong He, Chao Cai, Jiajuan Chen
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Atherosclerosis
Endothelial injury
MiR-483-5p
Autophagy
TIMP2
Online Access:https://doi.org/10.1186/s12872-023-03496-1

Internet

https://doi.org/10.1186/s12872-023-03496-1

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