Does denosumab exert a protective effect against COVID-19? Results of a large cohort study

Does denosumab exert a protective effect against COVID-19? Results of a large cohort study

IntroductionDenosumab is a monoclonal antibody blocking the receptor activator of nuclear factor kappa-B/receptor activator of nuclear factor kappa-B ligand (RANK/RANKL) pathway, thus inhibiting osteoclastogenesis. Since RANK and RANKL are also involved in the immune system activation, denosumab mig...

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Bibliographic Details
Main Authors: Sara Cassibba, Silvia Ippolito, Silvia Pellegrini, Roberto Trevisan, Alessandro Rossini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
denosumab
COVID-19
SARS-CoV-2
RANKL
osteoporosis
osteoimmunology
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1283101/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1283101/full

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