BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression.

Epigenetic mechanisms are essential for the regulation of all genes in mammalian cells but transcriptional repression including DNA methylation are also major epigenetic mechanisms of defense inactivating potentially harmful pathogens. Epstein-Barr Virus (EBV), however, has evolved to take advantage...

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Bibliographic Details
Main Authors: Anne Woellmer, Jose M Arteaga-Salas, Wolfgang Hammerschmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3435241?pdf=render