Vaccination and Omicron BA.1/BA.2 Convalescence Enhance Systemic but Not Mucosal Immunity against BA.4/5

Vaccination and Omicron BA.1/BA.2 Convalescence Enhance Systemic but Not Mucosal Immunity against BA.4/5

ABSTRACT Rising breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/5 led to the performance of various studies investigating systemic immunity and neutralizing antibodies in sera, but mucosal immunity remains understudied. In this cohort study, the...

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Bibliographic Details
Main Authors: Gabriel Diem, Michael Jäger, Stefanie Dichtl, Angelika Bauer, Cornelia Lass-Flörl, Markus Reindl, Doris Wilflingseder, Wilfried Posch
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
COVID-19 vaccines
neutralizing antibodies
Omicron BA.4/5
SARS-CoV-2
systemic/mucosal immunity
adaptive immunity
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05163-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05163-22

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