Enhanced thermodynamic, pharmacokinetic and theranostic properties of polymeric micelles via hydrophobic core-clustering of superparamagnetic iron oxide nanoparticles

Enhanced thermodynamic, pharmacokinetic and theranostic properties of polymeric micelles via hydrophobic core-clustering of superparamagnetic iron oxide nanoparticles

Abstract Background Superparamagnetic iron oxide nanoparticles (SPIO) have been applied for decades to design theranostic polymeric micelles for targeted cancer therapy and diagnostic MR imaging. However, the effects of SPIO on the physicochemical, and biological properties of polymeric micelles hav...

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Bibliographic Details
Main Authors: Yixin Jiang, Junghan Lee, Jin-Myung Seo, Enkhzaya Davaa, Kyung-Ju Shin, Su-Geun Yang
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-03-01
Series:Biomaterials Research
Subjects:
Polymeric micelles
Superparamagnetic iron oxide
Critical micelle concentration
Theranostic nanoparticle
Micelle stability
SPIO clustering
Online Access:https://doi.org/10.1186/s40824-022-00255-9

Internet

https://doi.org/10.1186/s40824-022-00255-9

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